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带状疱疹后神经痛（postherpetic neuralgia，PHN) 定义为带状疱疹 (Herpes Zoster, HZ) 皮瘆愈合后持续 1 个月及以上的疼痛，是带状疱疹最常见的并发症。 带状疱疹 相关性疼痛（ZAP）包括急性期疼痛和 带状疱疹后神经痛（PHN）。 带状疱疹 急性期疼痛是指 带状疱疹 发病后至皮损愈合期间的疼痛；而 PHN 是指皮疹愈合后持续 1 个月及以上的疼痛，是 带状疱疹 最常见的并发症。 带状疱疹后遗神经痛（Postherpetic neuralgia，PHN）是带状疱疹最常见的并发症之一，表现为剧烈的烧灼痛、感觉过敏和麻木，有些患者可持续终身，严重影响患者的生活质量，同时增加了医疗卫生资源的负担。
首次感染病毒之后，主要表现是水痘和潜伏状态。 潜伏状态的 VZV，受到一些诱因的刺激后，发生激活，而大量地复制，进一步在一些周围感觉神经及其所支配的单侧皮节处发生免疫反应，导致红斑、簇集性水疱以及神经痛 [2]。 此次我们特邀武汉协和医院陶娟主任，为我们讲解带状疱疹疼痛管理的病案分享和体会。 带状疱疹后遗神经痛是典型的神经病理性疼痛。 目前全球范围内医患双方对带状疱疹后遗神经痛治疗的满意度偏低，控制现状亟需改善。 那么，目前带状疱疹后遗神经痛的预防与治疗方面的新进展情况又是怎么样呢？
带状疱疹为什么会有神经痛呢? 神经是人体最娇嫩的组织，疱疹病毒对神经造成的伤害很难自我修复，可能两三个礼拜过去皮肤上的疱早就治好了，但病毒导致的神经痛没治好，给留下来了，就是带状疱疹后遗神经痛。
带状疱疹后遗神经痛一直是医学难题，但又十分常见，普瑞巴林的应用可获良效！ 专家简介： 罗文峰 主任 佛山市中医院，皮肤科主任助理，主任中医师，医学硕士，出身医学世家，毕业于广州中医药大学，师从著名皮肤性病学专家许德清教授和禤国维教授。 带状疱疹后神经痛（PHN）指带状疱疹皮瘆愈合后持续 1 个月及以上的疼痛，是带状疱疹最常见的并发症。 带状疱疹后神经痛是一种最常见的神经病理性疼痛，荟萃分析数据显示约 29.8% 的带状疱疹患者会发生 PHN。 什么是带状疱疹后神经痛，PHN 有哪些危险因素？ 此次我们特邀空军军医大学西京皮肤医院王刚院长，带领大家一起关注带状疱疹后神经痛的危险因素。
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