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Type b lactic acidosis is a rare and often fatal complication seen in patients receiving the nucleotide analogues zidovudine, stavudine, didanosine, and lamivudine. However, he added, he does take a patient’s kidney function into account, noting that lactic acidosis is a rare but possible complication of metformin use. There was no increased risk of developing acute kidney injury in the patients who were receiving metformin and no cases of lactic acidosis, and the rate of cardiogenic shock or death did not increase.
The available data suggest that the degree of lactic acidosis seen in diabetic patients taking metformin is similar to that in patients taking other antidiabetic medications (eg, sulfonylureas) or. Patients receiving sodium nitroprusside who show subsequent central nervous system dysfunction, cardiovascular instability, and increasing metabolic acidosis should be assessed for cyanide. A survey published a few years later found a majority of intensivists and nephrologists used iv bicarbonate to treat metabolic acidosis while the surviving sepsis campaign guidelines for the.
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