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A recent study reveals why most animals, including humans, inherit mitochondrial dna solely from their mothers, showing that retaining paternal mitochondria can harm development and health. Mitochondrial dna (mtdna) is inherited maternally across animals, yet the evolutionary rationale behind this unusual mode of inheritance remains a longstanding mystery Scientists have found a clue to why one type of dna is passed down to children by their mothers — but not their fathers
Mitochondrial dna is inherited only from the mother because the large female gamete (the egg) contains all the mitochondria for the zygote, while the smaller male gamete (the sperm) does not contribute mitochondria Essential functions of mitochondria the genes contained within the mitochondrial dna are directly linked to the cell’s energy supply. Scientists have long wondered why animals get the dna inside their mitochondria, the cell’s energy center, only from their mothers
New research explains why and offers hope for treating mitochondrial disorders.
Evolutionary evidence supported by the endosymbiotic theory identifies mitochondria as an organelle that could have descended from prokaryotes This may be the reason for the independent function and inheritance pattern shown by. This process ensures that the vast majority of the offspring’s mitochondria originate only from the mother’s egg cell This systematic elimination ensures a single, maternal line of inheritance for the mtdna
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