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This registration process only needs to be completed once The cancer mutation census (cmc) project is an undertaking to classify coding mutations in cosmic and identify variants driving different types of cancer. Please contact us via cosmic@sanger.ac.uk if you encounter any issues.
Cosmic mutational signatures is a catalogue of curated reference mutational signatures Cosmic_cancergenecensus_tsv_v102_grch37.tar release date may 21, 2025 genome Curation covers aetiology, acceptance criteria, tissue distribution and other genomic features of each mutational signature
Downloadable signature profiles and other data are freely available.
The aim of cosmic mutation actionability in precision oncology product (actionability) is to indicate the availability of drugs that target mutations in cancer and track the progress of clinical studies towards making new drugs available. Cosmic, the catalogue of somatic mutations in cancer, is the world's largest and most comprehensive resource for exploring the impact of somatic mutations in human cancer. Cosmic_cancergenecensus_tsv_v101_grch37.tar release date nov 19, 2024 genome
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