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We also summarize the current knowledge of the dynamics of mirna action and of the secretion, transfer, and uptake of extracellular mirnas. Here, we summarize the current understanding of mirna biogenesis, function and regulation, and outline challenges to address in the future. A thorough understanding of mirna biosynthesis and the distinct pathways involved in both animal and plant cells is of paramount importance for fully elucidating the regulatory networks that control gene expression and maintain cellular homeostasis.
Microrna, or mirna, is a small strand of rna that controls gene expression Pirna, mirna, and sirna have in common their short length and ability to silence genes. Gene expression here refers to how much of the corresponding protein is made from a gene.
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