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Learn how to interpret your sdma results for cats and dogs A key advantage of the novel gfr marker, sdma, is that it is not influenced by body muscle mass, meaning that it may provide a more accurate representation of renal function, particularly in patients with appreciable muscle loss (e.g., geriatric cat with ckd). Follow this algorithm to determine if kidney disease is probable and what steps you should take.
Sdma or symmetric dimethylarginine is a biomarker and amino acid arginine that contains two methyl groups in a symmetrical orientation which is excreted by kidneys Unlike other traditional markers, such as blood urea nitrogen (bun) and creatinine, sdma specifically measures kidney function in dogs. It gives more accurate and reliable value of glomerular filtration rate (gfr) than creatinine in dogs and cats.
What does it mean if my dog’s sdma result is raised
An increased sdma result reflects an impaired filtration rate of the kidneys, one of the first signs of kidney disease. We've had a wonderful and productive fall season in the school district of the menomonie area Sdma is a naturally occurring amino acid found in the blood It is a byproduct of protein metabolism and is normally filtered out by the kidneys
When kidney function declines, the kidneys become less efficient at filtering sdma, causing its levels to rise in the blood. Sdma (symmetric dimethylarginine) is the amino acid, arginine, that contains two methyl groups (dimethyl) in a symmetrical orientation Sdma is considered a sensitive and early marker (more sensitive than serum creatinine) of declining gfr in dogs and cats (hokamp and nabity 2016 review). It forms when arginine residues within proteins are methylated, a process catalyzed by protein arginine methyltransferases (prmts).
Monitor kidney function in cats and dogs with idexx sdma testing
Find everything you need to use, implement, and order sdma here. Sdma, short for symmetric dimethylarginine, is an important biomarker in veterinary medicine
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